Participants from Australia to Zambia attended the HIV prevention works, an official satellite symposium of the Eleventh International Conference on AIDS, held on July 6, 1996 in Vancouver, British Columbia. The symposium highlighted what works in HIV prevention, why sound HIV prevention programs and policies are public investments, and where attention should be directed in the future. This brief encapsulates the lessons learned and recommendations, which, a year later, have not lost their validity or relevance. The symposium was designed to profile international best practices, including models of successful HIV/AIDS prevention programs and policies, and to share and deepen knowledge about those programs and policies. Presentations were made on preventing HIV infection, consequences and conditions of risk, working with individuals and families, working with communities, working with organizational and societal change, and research for prevention evaluation.