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Impact of Intermittent Screening and Treatment for Malaria among School Children in Kenya : A Cluster Randomized Trial

ACADEMIC ACHIEVEMENT ACCESS TO FOOD ACCESS TO TREATMENT ACHIEVEMENT ACHIEVEMENT TESTS ADJUSTMENT ADOLESCENTS AGED AMODIAQUINE ANEMIA ANEMIA CONTROL ANOPHELES MOSQUITOES ANTENATAL CARE ARITHMETIC ATTENTION BASIC EDUCATION BASIC EDUCATION SECTOR BLIND BLOOD SAMPLES BURDEN OF MALARIA CERVICAL CANCER CHILD DEVELOPMENT CHILDHOOD CLASSROOM COGNITION COGNITIVE DEVELOPMENT COGNITIVE IMPAIRMENT COGNITIVE PERFORMANCE COMPARATIVE EDUCATION DEWORMING DIAGNOSIS DIAGNOSTIC TESTS DISEASE DISEASE BURDEN DROWNING DRUG ADMINISTRATION DRUG RESISTANCE DRUG TREATMENT DRUGS EDUCATIONAL ATTAINMENT EDUCATIONAL OUTCOMES EDUCATIONAL PERFORMANCE EFFECTIVE EDUCATION EFFECTIVE TEACHING ENROLLMENT EPIDEMIOLOGY ETHICS EXAM FEMALE ADOLESCENTS FEMALES FREE SCHOOLS GAMETOCYTE CARRIAGE GOVERNMENT PRIMARY SCHOOLS HEADACHE HEALTH FACILITY HEALTH INTERVENTIONS HEALTH OUTCOMES HEALTH SURVEYS HEALTH WORKERS HEMOGLOBIN CONCENTRATION HIGH MALARIA TRANSMISSION HIGH RISK OF INFECTION HIV HUMAN BIOLOGY HYGIENE IMPACT OF MALARIA INFANTS INFECTION INFECTION RATES INFECTIONS INFORMED CONSENT INTERVENTION IRON LEARNING LEUKEMIA LITERACY LITERACY INSTRUCTION LYMPHATIC FILARIASIS MALARIA MALARIA CONTROL MALARIA DIAGNOSIS MALARIA ENDEMIC COUNTRIES MALARIA IN PREGNANCY MALARIA INFECTION MALARIA INFECTIONS MALARIA INTERVENTIONS MALARIA MORBIDITY MALARIA PARASITES MALARIA PREVENTION MALARIA SYMPTOMS MALARIA TRANSMISSION MALARIA TREATMENTS MALARIA-ENDEMIC AREAS MASS SCREENING MEDICAL RESEARCH MENTAL DEVELOPMENT MIGRATION MODELING MORBIDITY MORBIDITY AND MORTALITY MORTALITY MOSQUITO NET NATIONAL SURVEILLANCE NEGATIVE EFFECTS NUMERACY NURSES NUTRITION NUTRITIONAL STATUS OLDER CHILDREN PARASITIC INFECTIONS PARASITOLOGY PARENTAL EDUCATION PNEUMONIA POLYMERASE CHAIN REACTION PREGNANCY PREGNANT WOMEN PREVALENCE PREVENTION OF MALARIA PREVENTIVE TREATMENT PRIMARY SCHOOL PRIMARY SCHOOL ACCESS PRIMARY SCHOOLING PRIMARY SCHOOLS PROPHYLAXIS PUBLIC HEALTH SCHOOL HEALTH SCHOOL QUALITY SCHOOLING SCREENING SEX SIBLINGS SOCIAL SCIENCE RESEARCH STOMACH TEACHER EDUCATION TEACHERS TEACHING METHODS THERAPY TRAUMA TREATMENT TREATMENT OF MALARIA TROPICAL DISEASES TROPICAL MEDICINE VECTORS VOMITING WORKERS YELLOW FEVER Microdata Set
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World Bank, Washington, DC
Africa | Kenya
2014-03-18T21:32:22Z | 2014-03-18T21:32:22Z | 2014-02

This paper investigates the effects of intermittent screening and treatment of malaria on the health and education of school children in an area of low-to-moderate malaria transmission. A cluster randomized trial was implemented with 5,233 children in 101 government primary schools on the south coast of Kenya in 2010-12. The intervention was delivered to children randomly selected from classes 1 and 5 who were followed up twice across 24 months. Once during each school term, public health workers used malaria rapid diagnostic tests to screen the children. Children who tested positive were treated with a six-dose regimen of artemether-lumefantrine. Given the nature of the intervention, the trial was not blinded. The primary outcomes were anemia and sustained attention and the secondary outcomes were malaria parasitaemia and educational achievement. The data were analyzed on an intention-to-treat basis. Anemia in this setting in Kenya, intermittent screening and treatment, as implemented in this study, is not effective in improving the health or education of school children. Possible reasons for the absence of an impact are the marked geographical heterogeneity in transmission, the rapid rate of reinfection following artemether-lumefantrine treatment, the variable reliability of malaria rapid diagnostic tests, and the relative contribution of malaria to the etiology of anemia in this setting.

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